Application Support Engineer

Salary: £75,000 - 75,000 per year

Requirements:

• Hands-on experience deploying, managing, and scaling multi-user applications on Kubernetes.
• Proven track record building continuous deployment pipelines using tools such as GitHub Actions, GitLab CI, ArgoCD, or Jenkins.
• Experience implementing and analyzing container and dependency security scanning tools.
• Proficiency with Terraform, OpenTofu, or similar tools for provisioning repeatable environments.
• Practical experience configuring Single Sign-On (SSO) and directory integration via SAML 2.0 / OIDC, such as Okta or Azure AD/Entra ID.
• Proficiency in Python, Bash, or Go to automate maintenance routines and internal workflows.
• Nice to have: hands-on experience with GitOps tools like ArgoCD or Flux for declarative state enforcement.
• Nice to have: experience backing up, restoring, and tuning databases commonly used by self-hosted applications, such as PostgreSQL, MySQL, or Redis.
• Nice to have: experience using monitoring, alerting, and logging tools.
• Ability to come into the office 3 days a week under a hybrid working model.

Responsibilities:

• Own, secure, and scale our suite of internal, multi-user tools and applications.
• Be responsible for vendor applications that we deploy in our own environments.
• Bridge the gap between Integration, Operations, and Security.
• Manage the full software lifecycle, from configuring secure cloud environments to executing continuous updates with minimal downtime.
• Deploy, upgrade, patch, and maintain multi-user self-hosted software instances across cloud environments.
• Plan and execute seamless, low-downtime application maintenance and database migration windows.
• Integrate with customer identity platforms to provide secure access.
• Configure monitoring and alerting, with runbooks for application health management.
• Build and maintain continuous deployment pipelines to automate application delivery, primarily for Kubernetes.
• Maintain Infrastructure-as-Code (IaC) templates and configuration management scripts for reliable instance provisioning.
• Integrate continuous security scanning into pipelines to inspect application code, dependencies, and container images for vulnerabilities.
• Remediate identified CVEs and enforce compliance and security standards across all internal platform tooling.
• Configure Single Sign-On (SSO), Role-Based Access Control (RBAC), and directory integration for onboarded applications.
• Automate and manage software rollouts across desktop fleets, headless Linux machines, and cloud environments using modern deployment pipelines and configuration tools.
• Enforce security baseline configurations, secrets management, and access controls for all newly introduced software packages.

Technologies:

• AI
• ArgoCD
• Azure
• Bash
• Cloud
• GitHub
• GitLab
• GitOps
• Support
• Jenkins
• Kubernetes
• Linux
• Machine Learning
• MySQL
• PostgreSQL
• Python
• RBAC
• Redis
• SAML
• Security
• Terraform
• Windows
• CI/CD
• LESS

More:

We are Isomorphic Labs (IsoLabs), launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. We apply frontier AI to drug discovery to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines, with an ambition to solve all disease. Our interdisciplinary team of drug discovery experts and machine learning specialists is building a world-leading drug design engine and continually innovating on model architecture to advance rational drug design. We value thoughtful, brave, determined, and collaborative ways of working, and we support an environment where learning is shared and every employee feels able to thrive. We offer a hybrid working model and would require you to be in the office 3 days a week, currently Tuesday, Wednesday, and one other day depending on the team. We are committed to equal employment opportunities and are happy to discuss accommodations if you have additional needs.

last updated 36 week of 2026